THE HISTORY OF MEC: AN EVOLVING CONSTRUCTION SITE
Imagine the extracellular matrix (ECM) as a giant construction site evolving over time. In the beginning, the construction site was poorly organized: the first cells behaved like individual isolated workers, each focused on his or her own task with no structural connection. There were no roads, scaffolding, or tools to coordinate activities.

As things evolved, however, the construction site began to organize. The first infrastructure, roads, cranes and scaffolding were built. This system not only allowed the "workers" (the cells) to communicate and collaborate, but also created a dynamic and functional environment capable of supporting complex buildings such as tissues and organs. MEC, from a simple filler, became a vital system for the growth and health of the whole organism.

THE FUNCTION OF THE MEC: THE HEART OF THE CONSTRUCTION SITE
On a well-organized construction site, roads enable the transportation of materials, scaffolding provides support for buildings under construction, and signals regulate traffic and activities. Similarly, MEC performs three main functions:
Structural: scaffolds (the collagen and elastic fibers) provide support and flexibility to tissues, just as a crane supports a structure under construction.
Of communication: biochemical signals travel through the MEC like directions on road signs, guiding cells on what to do and when to do it, such as repairing damage or starting new growth.
Transportation: like trucks transporting materials to the construction site, MEC facilitates the movement of nutrients, oxygen, and waste between cells and the circulatory system.

THE MAIN COMPONENTS OF MEC: THE TOOLS OF THE CONSTRUCTION SITE

Collagen: the steel beams
It provides strength and durability, just like the beams that support a building.

Elastin: the flexible cables
It allows the structure to bend without breaking, adapting to different stresses.

Glycosaminoglycans (GAGs): the water reservoirs
They retain large amounts of water, hydrating tissues and keeping the structure soft and resilient.

Proteoglycans: the foundation
They provide stability by binding the major components and ensuring that the system is cohesive.

Connective cells: site workers
Fibroblasts build fibers, mast cells activate defenses in an emergency, and macrophages clean up debris, keeping the yard orderly.

WHEN THE CONSTRUCTION SITE CRASHES: STRESS AND DYSFUNCTION
Under conditions of stress, chronic inflammation, lymphatic stasis or excessive permeability, the construction site becomes blocked. Roads become clogged, scaffolding weakens, and workers cannot coordinate. MEC loses its ability to support, nourish and protect cells.
Lymphatic stasis: fluid drainage slows, causing waste and toxin accumulation.
Excessive permeability: too much fluid and macromolecules leak from the vessels, filling the interstitial space and impairing communication between cells.
Inflammation: the environment becomes hostile, with signals that prevent regeneration and worsen tissue damage.

THE NUTRACEUTICAL PROTOCOL TO DECONGEST AND RESTORE THE FUNCTIONS OF THE MEC
To restore MEC function, action is needed on several fronts, using specific tools to decongest, stabilize, and reduce inflammation:

1. Cumaclean: decongestion and drainage
   • Improves lymphatic drainage, eliminating stagnant fluids and toxins.
   • Reduces stasis and reactivates lymphatic flow
   • Method of use: take 2 capsules in the morning with a glass of water.

1. Permeatonic: modulation of permeability
   • Regulates capillary permeability, preventing excessive leakage of fluids and macromolecules.
   • Restores the balance between compartments for an optimal cellular environment.
   • Method of use: take 2 capsules in the afternoon with a glass of water. 

1. Boswellia Plus: reduction of inflammation
   • Reduces silent cellular inflammation, promoting tissue repair and protecting collagen.
   • It enhances tissue regeneration, facilitating the recovery of MEC function.
   • Directions: take 1 tablet daily, preferably in the evening, with a glass of water.

4. Vitamin C Natural Plus: Collagen Production

1. • Promotes collagen production, ensuring the strength and resilience of tissues.
   • It is required for the synthesis of hydroxyproline, a key amino acid for the stability of the collagen triple helix.
   • It protects MEC from oxidative stress by neutralizing free radicals and preventing deterioration of its major components.
   • It enhances tissue regeneration, creating a more favorable environment for recovery and repair.
   • Directions: chew 1 tablet of Vitamin C Natural Plus daily, preferably in the morning, with a glass of water.

The ECM is the heart of our body's worksite-an organized system that connects, supports, and protects cells. When the worksite becomes blocked, the protocol with Cumaclean, Permeatonic, Boswellia Plus and Vitamin C Natural Plus is the targeted intervention to restore order and function, decongesting, stabilizing and reducing inflammation. In this way, MEC can once again become the foundation of health and well-being for the whole body.

Dr. De Vettor's supplements can be purchased at this site.

Disclaimer:

Before you begin taking any supplement, it is imperative that you consult your physician or a specialist to see if it is appropriate for your health condition. The directions provided are for informational purposes only and are in no way a substitute for medical advice. No liability is accepted for improper use of supplements and for any consequences of applying the information received without proper medical supervision.